Comparison of Efficacy between Gardasil and Cervarix towards Prevention of Cervical Disease: A Systematic Review

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W Ho
J Bhank
CY Chen
CK Fung
J Gan
L Jones
JS Ahn
Kwok G
C Lai
J Li
J Lim
H Ra
JH Yoo

Abstract

Cervical cancer is the second most common and the fifth deadliest cancer in women. Itaffects about 20 in 100,000 women per year and kills about 9 in 100,000 per year (CancerResearch UK, 2013). The 5-year survival rate is 80 to 90% and 60 to 75% for women withstage I cancer and stage II cancer respectively. This further decreases to 30 to 40% forwomen with stage III cancer and 15% or less for those with stage IV cancer (CancerResearch UK, 2013). The risk factors for cervical cancer include smoking, unprotected sexand socioeconomic factors, with Human Papillomavirus (HPV) being the most significantcontributor. HPV-16/18 has been shown to play a causal role in cervical cancer, causingabout 70% of all cases. (Schiffman, Castle, Jeronimo, Rodriguez, & Wacholder, 2007).

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How to Cite
Ho, W., Bhank, J., Chen, C., Fung, C., Gan, J., Jones, L., Ahn, J., G, K., Lai, C., Li, J., Lim, J., Ra, H. and Yoo, J. (2013) “Comparison of Efficacy between Gardasil and Cervarix towards Prevention of Cervical Disease: A Systematic Review”, Journal of Asian Medical Students’ Association. Kuala Lumpur, Malaysia, 2(3). Available at: https://jamsa.amsa-international.org/index.php/main/article/view/31 (Accessed: 18April2021).
Section
Review Article