Comprehensive Assessment of Risk Factors Associated with Methicillin-Resistant Staphylococcus aureus (MRSA) Infection in Asia: A Systematic Review

Main Article Content

Gilbert Lazarus
Jessica Audrey


Background Antibiotic resistance persists as a global health challenge, among which methicillin-resistant Staphylococcus aureus (MRSA) is the most common and serious threat. Although certain control strategies have been implemented, the incidence and prevalence of MRSA remain high, especially in Asia

Objective To analyze the risk factors associated with MRSA infection in Asia

Methods A systematic review was conducted through PubMed, Scopus, and EBSCOhost, searching for observational studies which analyze the risk factors associated with MRSA infection in Asia. Studies selected were reviewed and assessed with STROBE’s criteria.

Results Sixteen observational studies were included, with a total of 10,253 subjects, consisting of 4 cohort studies, 4 cross-sectional studies, and 8 case-control studies. We find that certain social behaviors, such as sharing of personal items, limited daily activities and exposure to post-surgery individuals increases the risk of MRSA infection. Antibiotics use, especially when used extensively, is also found to elevate the risk. Furthermore, invasive medical procedures ease the entry of MRSA into the body, thus increasing risk of infection.

Conclusion The knowledge of these factors is hoped to help in establishing guidelines for infection prevention and control strategies, helping to halt the rise in antibiotics resistance, as well as reducing the prevalence of MRSA infection worldwide.

Article Details

How to Cite
Lazarus, G. and Audrey, J. (2019) “Comprehensive Assessment of Risk Factors Associated with Methicillin-Resistant Staphylococcus aureus (MRSA) Infection in Asia: A Systematic Review”, Journal of Asian Medical Students’ Association. Kuala Lumpur, Malaysia, 7(1). Available at: (Accessed: 6July2022).
Review Article


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